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Nephrology Journal Club on Twitter: "Difelikefalin (CR845) (KORSUVA) is a  peripherally restricted, selective kappa opioid receptor agonist that  exerts antipruritic effects by means of activation of kappa opioid receptors  on peripheral neurons
Nephrology Journal Club on Twitter: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

Topical administration of the kappa opioid receptor agonist nalfurafine  suppresses corneal neovascularization and inflammation | Scientific Reports
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports

Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role |  Semantic Scholar
Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role | Semantic Scholar

Frontiers | A Review of the Therapeutic Potential of Recently Developed G  Protein-Biased Kappa Agonists
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Down-regulation of kappa opioid receptor promotes ESCC proliferation,  invasion and metastasis via the PDK1-AKT signaling pathway | Cell  Communication and Signaling | Full Text
Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text

Biased ligands at opioid receptors: Current status and future directions |  Science Signaling
Biased ligands at opioid receptors: Current status and future directions | Science Signaling

Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and  Back
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back

The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology  of Schizophrenia: A Review of the Evidence - ScienceDirect
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence - ScienceDirect

Kappa Receptors – Opioid Peptides
Kappa Receptors – Opioid Peptides

HTRF Tag-lite Opioid Delta & Kappa receptors fluorescent probe
HTRF Tag-lite Opioid Delta & Kappa receptors fluorescent probe

IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake  Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following  Chronic Intermittent Ethanol Exposure
IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure

Opioids in cancer: The κ‑opioid receptor (Review)
Opioids in cancer: The κ‑opioid receptor (Review)

Table II from Systemic kappa opioid receptor agonists in the treatment of  chronic pruritus: a literature review. | Semantic Scholar
Table II from Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: a literature review. | Semantic Scholar

Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or  approach-avoidance behavior occur differentially across the nucleus  accumbens shell rostro-caudal axis - ScienceDirect
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect

κ-Opioid Receptor (KOP) | 7TM Antibodies
κ-Opioid Receptor (KOP) | 7TM Antibodies

Structure of the human κ-opioid receptor in complex with JDTic | Nature
Structure of the human κ-opioid receptor in complex with JDTic | Nature

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment - ScienceDirect
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect

Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications  for negative affective states and psychiatric disorders - ScienceDirect
Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications for negative affective states and psychiatric disorders - ScienceDirect

Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED

Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the  Brain
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain

The blocking of kappa‐opioid receptor reverses the changes in dorsolateral  striatum dopamine dynamics during the amphetamine sensitization - Azocar -  2019 - Journal of Neurochemistry - Wiley Online Library
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library

Activation of kappa opioid receptor (KOR) signaling increases... | Download  Scientific Diagram
Activation of kappa opioid receptor (KOR) signaling increases... | Download Scientific Diagram

Kappa Opiate Receptor Agonist - an overview | ScienceDirect Topics
Kappa Opiate Receptor Agonist - an overview | ScienceDirect Topics