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Nephrology Journal Club on Twitter: "Difelikefalin (CR845) (KORSUVA) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports
Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role | Semantic Scholar
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text
Biased ligands at opioid receptors: Current status and future directions | Science Signaling
Frontiers | The Kappa Opioid Receptor: From Addiction to Depression, and Back
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence - ScienceDirect
IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure
Opioids in cancer: The κ‑opioid receptor (Review)
Table II from Systemic kappa opioid receptor agonists in the treatment of chronic pruritus: a literature review. | Semantic Scholar
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
κ-Opioid Receptor (KOP) | 7TM Antibodies
Structure of the human κ-opioid receptor in complex with JDTic | Nature
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect
Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications for negative affective states and psychiatric disorders - ScienceDirect
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Frontiers | Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library